常规人型-PPD、BCG-PPD、PHA三联皮肤试验的临床应用及评价

CLINICAL APPLICATION AND EVALUATION OF ROUTINE SKIN TEST OF HUMAN-PPD,BCG-PPD AND PHA

对1097例门诊和住院病人进行常规人型-PPD、BCG-PPD、PHA三联皮肤试验。结果表,患病人群中PPD强阳性率随年龄增长而增高,高峰年龄30～50岁,患病人群平均PPD强阳性率为26.07％～31.09％;PHA阳性率为79.58％;临床疑诊结核病、购膜炎、消化道疾患等PPD阳性率较高;12岁以下小儿一般阳性率显著低于全国卡介苗保护率平均水平。常规PPD检测不仅对结核病早期诊断、细胞免疫功能评价有重要意义,而且在评价卡介苗接种效果、及时发现漏种病例、提高整体免疫水平方面亦有重要价值。

A routine skin test of human-PPD. BCG-PPI) and PHA was performed in 1 097 out-patients and in-patients. The results showed that the intensely positive rate of PPD in the patients increased with age ,the highest rate was between the ages of 30 and 50 years . The average rate of intense positiveness of PPD was 26. 07%-31. 09%,and that of PHA was 79. 58%. The higher positive rate of PPD was such diseases as tuberculosis in suspect,pleurisy,gastrointestinal diseases and so on. The positive rate of children below age 12 was obviously lower than the average level of the protective rate of BCG in the nation. Making the routine PPD measurement had important value and significance not only in earlier diagnosis of TB and evaluation of cell immune function,but aiso in evaluation of BCG vaccinal results,timely discovery of non-vaccinated cases and increase of the whole level of immunity.