乳头溢液良恶性病变的病理组织学研究

PATHOLOGICAL STUDY IN BENIGN AND MALIGNANT ORIGINAL LESIONS OF NIPPLE DISCHARGE

本研究对１９９４年２月～１９９５年１月天津市肿瘤医院乳腺科连续收治的以乳头溢液为主诉患者８４例病变区段切除标本的次连续大块病理切片进行病理组织学观察。结果发现，此８４例患者１１例为癌，其中８例为Ｔ０癌，占全部无肿瘤溢液患者６６例的１２．１２％，因大多数为较早期癌，故检出此期癌早诊意义重大。另外，导管内乳头状瘤５０例，占５９．５２％，且发现导管内乳头状瘤常与中及重度乳头状瘤病并存。考虑发生在大导管的乳头状瘤与中小导管发生的乳头状瘤病可能是同一致病因素作用下所发生的同类病变，且二者均可癌变，故应当重视这些病变的检出和处理。

Between Fab.1994 and Jan。l995 ,a pathological study with subserial sectioning for resected specimens was performed in 84 consecutive patients with nipple discharge as the main clinical manifestation, The result showed that in the 84 patlents,1here were l i cases of breast carcinoma including 8 To carcinoma which accounted for 12.12%of all the 66 patients without neoplastic discharge。lt is of important significane to detect such lesions because most of them were in the early stages。 Fifty cases of intraductal papilloma(59.92%)were found in the 84 patients; multiple intraductal papilloma was often associated with moderate and severe papillomatosis。 lt is posslble that intraductal papilloma arising in the large ducts presents with the same kind of pathologic changes and occurs under the same kind of pathogenic factors aspapillomatosis arising in the middling and small ducts, Great attention should be paid tthe detection and management of the diseases。