摘要
我国南方民间常用黄皮[Clausena Lansjum(Lour.)Skeels]叶治疗肝炎、糖尿病等。黄皮香豆精是从黄皮叶分离出的一种呋喃香豆精类化合物,结构见图1,其药理作用未见报道。本文用正常小鼠及四氧嘧啶高血糖小鼠观察了黄皮香豆精的降血糖作用和对血乳酸的影响。
Clausenacoumarine is a compound isolated from the leaves of Clausena lansium (Lour.) Skeels which grows widely in South China. The studies show that clausenacoumarine can lower blood glucose level in normal mice and alloxan diabetic mice at 200 mg/kg.d for three days orally, and antagonize the elevation of blood glucose caused by injecting adrenaline in normal mice. No effect on blood lactic acid was observed.
出处
《药学学报》
CAS
CSCD
北大核心
1989年第5期391-392,共2页
Acta Pharmaceutica Sinica
关键词
黄皮香豆精
降血糖作用
血乳酸
Clausenacoumarine
Hypoglycemics
Blood glucose
