犬重度呼吸道蒸汽烧伤48h内肾脏的组织学和超微结构观察

Histopathological and Ultrastructural Studies of Renal Tissues in Dogs with Severe Steam Respiratory Burns

本文对犬重度呼吸道蒸汽烧伤48h内肾脏标本进行了组织学和超微结构观察,结果表明:复合组和单呼组病变基本相似。肾血管球细胞可表现两方面的变化:一是细胞肥大和/或增生,前者表现为细胞肿大,胞质增多,富含细胞器;二是细胞退变,主要为细胞内水肿。细胞内水肿,复合组较单呼组为多见。肾小管显示不同程度的变性、坏死及管型形成。小管坏死多累及近曲小管。文中对近曲小管坏死的发生因素进行了简要讨论。

This paper is to report the pathological changes in canine renal tissues after severe steam inhalation injuries. The specimens from 84 male mongrel dogs are studied with a light microscope, and 30 tissue samples of the 84 with an electron microscope. The morphological changes of glomeruli are characterized by, hypertrophy and/or hyperplasia of the glomerular cells, the former manifested as cell enlargement, increased amount of cytoplasm and rich in organelles; retrogressive changes of the glomerular cells in varying degrees as evidenced by intra-cellular edema. The renal tubules show varying degrees of degeneration, necrosis, and casts formation. Tubular necrosis affects more frequently the proximal convoluted tubules. The etiological factors of it are briefly discussed.