摘要
本文研究了稀有鲫(Gobiocyprisrarus)作为毒性试验材料的可行性。采用换水式试验,在硬度为200mg/L(以CaCO3计)、pH7.8±0.2、温度24-25℃条件下研究了铬、铜、锌和五氯酚(PCP)对稀有鲫的急性毒性。重铬酸钾对2日龄稀有鲫的24h和96h和LC50控制范围分别263.6-334.7和1153-178.5mg/L(n=8)。铬、铜、锌和五氯酚对2日龄稀有鲫的急性毒性值(96hLC50)范围,从铜的52.2μg/L到铬的52000μg/L,毒性大小的顺序是铜>五氯酚>锌>铬。研究结果表明,稀有鲫有可能发展成为一种较为理想的毒性试验材料。
This study deals with the evaluation of Gobiocypris rarus as a toxicity test material The acute toxicity of chromium, copper,zinc and pentachlorophenol(PCP) to Gobiocypris rarus were determined under renewal condition with a hardness of 200 mg/L(as CaCO3) at pH7.8±0.2 in water held at 24-25℃.The control limits of 24h and 96h LC50 of potassium dichromate to 2 d old Gobiocypris rarus were 263.6-334.7 and 115.3-178.5 mg K2Cr2O7/L(n=8).The values of the acute toxicity(96h LC50) to 2 d old Gobiocypris rarus ranged from 52.2 μg/L for copper to 52000 μg/L for chromium,and were ranked in order of toxicity:Cu>PCP>Zn>Cr.The results of this study indicated that Gobiocypris rarus may be a proper animal for toxicity test.
关键词
稀有Qu鲫
急性
毒性
铬
铜
锌
五氯酚
实验动物
Gobiocypris rarus
Acute toxicity
Chromium
Copper
Zinc
Pentachlorophenol