微波对小白鼠超氧化物歧化酶和脂质过氧化物的影响

EFFECTS OF MICROWAVE IRRADIATION ON SUPEROXIDE DISMUTASE AND LIPID PEROXIDE PRODUCTS IN MICE

低剂量（９１５兆赫）的微波照射小白鼠后，用ＮＢＴ光化还原法测知脾脏的ＳＯＤ活性降低；聚丙烯酰胺凝胶电泳ＰＡＧＥ测知ＳＯＤ的电泳图谱发生了变化；脂质过氧化物增加。经恢复饲养，ＳＯＤ的活性持续下降，脂质过氧化物含量持续增高，但降低和增加的趋势于第１１天后趋于稳定，而ＳＯＤ的电泳酶谱却不能恢复到对照水平。本研究表明低剂量的微波照射对小白鼠的ＳＯＤ具有明显的损伤作用，并使有害于机体的脂质过氧化物增加。

In this expariment, the mice were irradiated by the low dose microwave, then we detected the activity of superoride dismutase(SOD)in the spleecn of the mice with NBT photoreduction method. We discovered that SOD PAGE patterns changed and lipid peroxide products(LPO)increased. During the recovery process, the SOD activities decreased continuously, the LPO increased continuously, on the eleventh day after the irradiation, the changes have become stable. But the SOD PAGE patterns did not recover to control level. The results show the physiological and biochemical function of mice can be clamaged by low dose microwave irradiation.