摘要
作者对广州地区百岁老人和健康的中青年人外周血淋巴细胞SCE频率和分布进行了检测。结果表明:百岁老人组SCE频率较中青年人组高(P<0.001),但两组SCE分布是相似的。且在各组染色体上以A组出现串为最高,后依次递减。未发现SCE频发于任何1号染色体。
A comparative study with the method of microscopic and photomicrographic karyotype analysis was carried out on SCE frequency of peripheral blood lymphocytes and chromosomal distribution of SCE between 3O centenarians (101-107 years old)and 34 healthy adults in Guangzhou area. The result showed that the frequency of SCE in centenarian group was remarkably higher than that in the healthy adult group (P<0.001) , but the chromosomal distribution of SCE in both groups was similar without statistic differnce (P>0.05); that the SCE frequency in group A was the highest with those in groups B, C, D, E, F and G being arranged in progressively decreasing order; that no frequent occurrence was seen on any code number of chromosome and chromosomal short or long arm, and the distribution of SCE in the cells of both groups was mainly on the chromosomal long arm, accounting for 76.18% of the total number of SCE; and that SCE was more common in terminal exchenge than in centromeric and interstitial exchange.
出处
《遗传与疾病》
CSCD
北大核心
1989年第1期9-11,63-64,共3页
