摘要
观察30例先心病伴肺动脉高压患者体外循环内皮素水平的变化,发现体外循环中、后早期内皮素明显升高,川芎嗪可明显减少内皮素的产生。
Changes of endothelin(ET)after cardiopulmonary bypass(CPB)in 30 patients with congenital heart disease with pulmonary hypertention were observed.The results showed that plasma ET rose significantly during and after CPB,meanwhile,plasma ET was reduced obviously due to use of tetramethylpyrazine.
关键词
体外循环
心脏病
肺动脉高压
内皮素
川芎嗪
cardiopulmonary bypass endothelin tetramethylpyrazine pulmonary hypertention