美丽红豆杉素B的全合成研究

Studies on the Total Synthesis of Taxamairin B

美丽红豆杉素Ｂ的全合成研究王学超，张驰，潘鑫复，陈耀祖（兰州大学化学系，应用有机化学国家重点实验室，兰州，７３００００）关键词美丽红豆杉素Ｂ，全合成，Ｆｒｉｅｄｅｌ－Ｃｒａｆｔｓ成环反应，选择性氧化化合物９（１０→２０）重排松香烷化合物是近年来被人们...

Taxamairin B,a novel rearranged 9(10→20)-abeo-8,11,13-triene diterpene,containing a tropone ring system has been synthesized from commercially available catechol and 1,3-cyclohexandione by a short and efficient route.A Friedel-Crafts annunation and the oxidation of the allylic and benzylic methylene group are the key steps.