摘要
对23个N-二茂铁甲酰基-N'-芳(烷,二茂铁)基硫脲和14个N-苯甲酰基-N'-芳基硫脲的δ_(β-NH)与各种取代胺的碱性强度pK_b及苯环上取代基常数σ进行了系统的定量关系研究。结果表明:酰基硫脲分子内氢键的强弱可由β-氮上氢原子的化学位移值(δ_(β-NH))来衡量。这类化合物分子内氢键的强弱(δ_(β-NH))与pK_b或σ之间有较好的线性关系,从而揭示了此类化合物的分子内氢键与取代基效应之间的定量关系.
The strength of intramolecular hydrogen bond of acyl thiourea can be monitored by the hydrogen chemical shiftδ(β-NH). We measured the physical properties of 23 N-ferrocenoyl-N'-aromatic(also alkyl,ferrocenyl) thioureas and 14 N-benzoyl-N'- aromatic thioureas including δ(β-NH),pKb in relation with the σ-parameter of substituents on the aromatic ring. We found that there are a good relationship between the strength of the intramolecular hydrogen bondδ(β-NH) and pKb or σ-parameter of the substituents, thus the substitution effect toword the hydrogen bonding can be revealed.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1995年第8期1233-1236,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
南开大学元素有机化学国家重点实验室资助.
关键词
酰基硫脲
分子内氢键
碱性强度
取代基常数
N-Ferrocenoyl(benzoyl)-N'- substituted thiourea, Intramolecular hydrogen bond,Thiourea derivatives,Basic strength,Substituent effect