摘要
合成了一种新型的双苯甲酰胺冠醚固定相:(1S,2S)-1-(对苯甲酰胺基)苯基-2-苯甲酰胺基-16-冠-5,其结构经红外光谱、核磁共振、质谱及元素分析数据证实。考察了这种固定相的柱效、热稳定性、极性及选择性等色谱特性。该类固定相对极性位置异构体分离效果良好。由于冠醚上引入苯甲酰胺取代基,因而对苯胺类及不经衍生化的碱性化合物能特殊选择性地分离。
A new kind of double benzamide crown ether:1S,2S-1-p-(benzamide)phenyl,2-Benzamide-16-crown-5 was synthesized for use as stationary phases in capillary column gas chromatography.Its structure was confirmed by IR, ̄1H NMR,MS and elemental analysis.The chromatographic characteristics,including column efficiency,thermal stability,polarity and selectivity were studied.Excellent selectivity was obtained for the separations of polar position isomers.The benzamide substituent group on crown ether makes the stationary phase have special selectivity for separating anilines and other basic compounds without derivatization.The factors which affect the separation mechanism, including dipole-dipole interactions,hydrogen bonding forces are discussed.
出处
《高等学校化学学报》
CSCD
北大核心
1995年第12期1878-1882,共5页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
气相色谱
毛细管柱
冠醚
固定相
Gas chromatography
Capillary column
Crown ether stationary phase