高血压患者及其子女红细胞膜ATP酶活性的研究

Erythrocyte Membrane ATPase Activities in Patients with Hypertension and Their Children

原发性高血压患者的红细胞膜Na^+-K^+-ATPase、Ca^(2+)Mg^(2+)-ATPase活性低于正常对照组，但和其子女的测定值无差异，不论EH患者和于女，两种酶活性的改变均与血压不相关。上述结果提示红细胞膜钠泵、钙泵活性低下是EM患者和子女共有的特性。但这种改变可能不是高血压的原因，也不能作为预测高血压发生、发展的参数。

Erythrocyte membrane Na^+-K^+-ATPase and Ca^(2+)-Mg^(2+)-ATPase activities in patient with EH are lower than that in controls,while no significant difference of those two ATPase activities was found between the parent patients and their children.Both Na^(2＋)-K^+-ATPase and Ca^(2＋)-Mg^(2＋)-ATPase are not correlated to blood pressure.The resuls indicate that the decreased erythrocyte membrane Na^+-K+-ATPase and Ca^(2＋)-Mg^(2＋)-ATPase activities maybe the common charcteristics of EH patients and their hildren.These properties may not be the causes for hypertension,nor be the predictors for the development of hypertension.