高原老年人右心室舒张功能的脉冲多普勒超声研究

A STUDY ON DIASTOLIC FUNCTION OF RIGHT VENTRICLE IN AGED AT HIGH ALTIUDE BY PULSE WAVE DOPPLER

海拔２２６０ｍ老年１３例（Ａ组），海拔３５００～４２００ｍ老年１２例（Ｂ组），年龄６０～７４岁。ＥＣＧ、ＵＣＧ、心三位片和肺功能无右室肥大和器质性心脏病及慢阻肺。脉冲多普勤测定三尖瓣口Ｅ＿ｖ、Ａ＿ｖ、Ｅ＿Ｉ、Ａ＿Ｉ、Ａ＿ｖ／Ｅ＿Ｉ、ＥＤＴ、ＡＴ。结果发现Ｂ组的Ａ＿ｖ／Ｅ＿ｖ增大（Ｐ＜０．００１）；ＥＤＴ及ＡＴ缩短（分别Ｐ＜０．００１）；ＡＴ与ＥＤＴ呈高度正相关（ｒ＝０．９３５、Ｐ＜０．０１）；ＡＴ与Ａ＿ｖ／Ｅ＿ｖ呈高度负相关（ｒ＝－０．９１６、Ｐ＜０．０１）；且ＥＤＴ与Ａ＿ｖ／Ｅ＿ｖ亦呈高度负相关（ｒ＝－０．９０７、Ｐ＜０．０１）；表明尚无高原心脏病的海拔３５００ｍ以上高原老年人，右室舒张功能减低，右室后负荷已有一定程度增加，两者间呈高度正相关关系。

3 cases in group A lived at 2 260m and 12 cases in group B at 3 500～4200m high altitude werestudied with Pulse Wave Doppler on right ventricle function. All of the subjects had no heart disease,RVH and COPD.The resu It wasthat 1,A_v/E_v increased,AT and EDT decreased in group B(P<0.001).2.a significant positive correlation betvveen AT and EDT(r=0.94,P<0.01)and a signlfi-cant negative correlation between AT and A_v/E_v(r=-0.92 ,P<0.01)in group B.3. a significantnegative correlation between EDTand A_v/E_v(r=0. 91 ,P<0. 01)in group B. It was suggested thatin the aged residing at 3 500m altitude and showing no high altituede heart disease,the afterload ofright ventricle was increased and the diastolic function of right ventricle was decreased.