原发性肝癌生长状态与宿主巨噬细胞活性研究

STUDY ON THE RELATIONSHIP BETWEERN THE GROWTH OF HEPATOCELLULAR CARCINOMA AND THE ACTIVITY OF MACROPHAGES(M/ φ)

通过手术观察49例原发性肝癌生长状态,研究机体Mφ活性与肝癌肝内播散的关系。发现包膜完整组Mφ活性显著高于不完整组;大肝癌组(直径>5cm)与小肝癌组(直径≤5cm)Mφ活性无显著差别;单个癌结节组与多个癌结节组Mφ活性亦无显著差别。提示Mφ活性与包膜完整性密切相关,Mφ有抑制肝癌肝内播散作用。

Relationship between M Φ activity and the growth of hepatocellular carcinoma (HCC) was been studied in 49 cases after operation. It was found that MΦ activity in the patients with tumor capsulated completely by fibrous tissue is significantly higher than that in the patients with tumor capsulated uncompletely. There is no significant difference on MΦ activity between the groups of large HCC and small HCC, and between groups of single nodule and multiple nodules. The results suggest that M Φ activity is closely related to the fibrous capsule of HCC, and MΦ maybe prevent HCC from spreading.