药物配方优化的计算机辅助设计研究Ⅱ─—序贯无约束极小化方法及其应用

The Sequential Unconstrained Minimization Techniques for the Design of Drug Compositions

应用序贯无约束极小化方法（也称混合罚函数法）于药物配方优化设计，设计的程序已在计算机上实现，其正确性和有效性通过实际优化例子得到了验证。

The Sequential Unconstrained Minimization Techniques based on nonlinear pra-gramming for the design of drug composotions is described. The example is also given to demon-strate the effectiveness of the method which can be used on computers.