摘要
用含猪血红细胞的灌流液对离体大鼠肝灌流方法进行了改进。以灌流期间ＬＤＨ、ＣＰＴ、葡萄糖、流量和胆汁分泌量的改变作为肝脏活力的评价指标，比较了用不含猪血红细胞的普通灌流液和含猪血红细胞的灌流液灌流的结果，结果表明用不含猪血红细胞的灌流液灌流，肝脏活性仅能维持２ｈ，而用含猪血红细胞的灌流液灌流，４ｈ内肝脏能保持正常活力。
he perfusion method of isolated rat liver was improved using with Krebs-Henseleit buffercontaining porcine erythrocytes.The liver was ditermined by observing the variabions of LDH, GPT,glu cose,flow rate and bile secreting during the porfusion.The resultes showed that the liver activity could maintain in normal for 4 hours when perfused with buffer containing porcine erythrocytes,but less than about 2hours with buffer not containing porcine erythrocytes.
出处
《广东药学院学报》
CAS
1995年第2期95-97,共3页
Academic Journal of Guangdong College of Pharmacy
关键词
肝脏
灌流
药理学
liver
perfusion
activity
porcine erythrocytes
