摘要
本文采用美国87400-000型骨环钻(内径约7.5mm)作髂骨骨活检,不脱钙骨组织切片,作骨组织计量学参数测定.结果表明:氮质血症期骨组织形态参数已显示异常,主要表现骨形成增加,成骨细胞活性增高,骨吸收正常。尿毒症早期骨形成及骨吸收均增加,骨小梁体积减少,骨矿化障碍。尿毒症晚期主要表现为骨吸收明显增加,骨矿化障碍严重。维持血透患者除骨吸收增加及骨矿化障碍外,还存在骨组织纤维化形成。
Ilia biopsy and bone histomorphometry was performed in 8 cases chronic renal failure(CRF).The resuIts showed:in patient with azotemia,bone formation was elevated; in patient withearly uremia ,bone formation and bone resorption were increased,the volume of bone trabecula was di-minished and bone mineralization disturbed;in patients with late stage uremia,bone resorption was re-markably increased and bone minerailzation seriously disturbed;besides,fibrcais in bone tissue was ob-served in a patient with maintenanced hemodialysis.
出处
《广东药学院学报》
CAS
1995年第2期82-84,共3页
Academic Journal of Guangdong College of Pharmacy
关键词
慢性
肾功能衰竭
骨组织
计量学
CRF(chronic renal failure)
ROD(renal osteodystrophy)
BH(bone histomor-phometry)