摘要
小鼠连续口饲山栀子水提物（７ｇ／ｋｇ·ｄ）５天，血清总胆红素水平明显降低，并可明显降低由四氯化炭（ＣＣｌ４）、硫代乙酰胺（ＴＡＡ）诱发的血清谷丙转氨酶（ＳＧＰＴ）升高；大鼠连续给山栀子水提物（１．５ｇ／ｋｇ·ｄ）４天，胆汁分泌量明显增加，加速注入胆红素的排泄。而口饲相同剂量水栀子水提物则无明显的上述作用。
Shanzhizi(Gardenia jasminodes ELLis)abstract given stomach perfusion daily dose of 7g/kg wt for five days in mice significantly decreased the total bilirubinin in serum and elevated alanine aminotransferase(ALT) induced by CCl4 and thioacetamide(TAA).Given daily dose of1.5g/kg wt for three days in rats it increased the biliary juice flow and accelerated plasma clearance of infused unconjuated bilirubin, while Shuizhizi(Gardenia jasminoides ELLis var. grandiflora) abstract was given in the same way,the action as above were not found.
出处
《广东医学院学报》
1995年第2期107-110,共4页
Journal of Guangdong Medical College
关键词
山栀子
水栀子
胆红素
谷丙转氨酶
栀子
药理学
shanzhizi/drug effect
shuizhizi/drug effect
bilirubin
SGPT
rats
mice
