小儿脑脊液细胞学186例次检查分析

Analysis of Cerebrospinal Fluid Cytology in 186 Children

采集１８６例次腰穿脑脊液标本，结果发现在受到特异性及非特异性刺激后，小儿脑脊液同样存在：转化型淋巴细胞或淋巴样细胞、单核样细胞、嗜中性粒细胞及混合性细胞等四种主要的细胞学反应。与成人不同的是，细胞分化率较高。在疾病不同时期，受治疗的影响，ＣＳＦＣ出现规律性变化。与脑脊液常规分类计数比较，其敏感性及可靠性较高，可直接检出病源体、肿瘤细胞及其它特异性细胞成分；对中枢神经系统出血、感染、肿瘤和脑膜白血病的诊断及评价疗效有较大的参考价值。

In order to study the changeful rule of cerebrospinal fluid cytology (CSFC). 186 preparation of cerebrospinal fluid (CSF) have been collected and examined, according to the cytological classification new concept of Hou Xider in CSF. The results showed: there were 137 cases with abno abnormity. Abnormity rate is 73.6%, of which 98 cases have diagnostic value, and the diagnostic accordance is 71.5%, As the same time. we found, when CSF was stimulated specificitly or nonspecificitly, The CSF of children show four main CSFC reaction, they were transformated lymphocyte or lymphoidocyte; mononuclear cell, neutrophilic leukocyte and mixed leukocyte reaction. Dynamic observation found in different period of disease and treated influence, CSFC had regularity alteration. It have higher sensitivity and reliability than CSF routine counting method. And we can directly find pathogen, tumor cell and another specificity cell. CSFC technique has bigger consult value in diagnose and therapeutic evaluation of central nervous system with bleeding, infection, tumor and meninges leukemia.