海南长须果化学成分的研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF TACCA CHANTRIERI ANDRE.IN HAINAN

从海南长须果（ＴａｃｃａｃｈａｎｔｒｉｅｒｉＡｎｄｒｅ）中分离得到了３个结晶性成分，经过理化常数和光谱分析，分别鉴定为箭根酮内酯Ａ（Ｉ）、１，７－二对苯羟墓－３，５－二羟基－庚烷（Ⅱ）和α－单棕桐酸甘油酯（Ⅲ）。它们均属首次从该植物中分得。其中箭根酮内酯Ａ有抗癌活性。

Three pure chemical compounds have been isolated from Tacca chantrieri Andre. Their structures have been determined as taccalonolide A (1), 1, 7-bis (4-bis (4-hydroxy-phenyl)-3, 5-heptanediol (2) and a-monopalmitin (3) by spectrometric analysis and physical chemical constants. They are all isolated for the first time from this plant. Taccalonolide A showed cytotoxic activity against P-388 leukemia in cell cultute.