参麦注射液对急性心肌梗塞患者超氧化物歧化酶影响的临床观察

Clinical Observation on the Influence of Shen Mai Injection to the SOD in the Patients with Acute Myocardial Infarction

将采用常规疗法加静脉滴注参麦注射液治疗的３０例（治疗组）急性心肌梗塞（ＡＭＩ）患者，与常规疗法治疗的１５例（对照组）作对照观察，两组治疗前后血中超氧化物歧化酶（ＳＯＤ）活性的变化。结果治疗前两组患者血中ＳＯＤ活性比较，经统计学处理，无明显差异（Ｐ＞０．０５）。治疗后治疗组患者血中ＳＯＤ活性明显提高。治疗后两组血中ＳＯＤ活性比较，有显著性差异（Ｐ＜０．０５）。对照组治疗后血中ＳＯＤ活性与治疗前比较略有降低，但无统计学意义（Ｐ＞０．０５）．提示参麦注射液可提高ＡＭＩ患者血中ＳＯＤ活性，对防治ＡＭＩ患者再灌注损伤，具有一定的临床意义。

With 30 cases of acute myocardial infarction(AMI) treated with conventional therapy and intravenous drip of Shen Mai Injection as treated group and 15 cases treated with conventional therapy alone as contral group,we examined the activity of superoxide dismutase(SOD)in the blood of both groups before and after treatment.The results,which were analysis by statistics,showed that there was no obvious difference (P>0.05)between the two groups before treatment.After treatmant,the activity of the SOD of the treated group increased distinctly.There was a significant difference (P<0.005) between the two groups.Although in the control group the activity of the SOD decreased slightly after treatment,there was no significant (P>0.05) in statistic.The results suggested that Shen Mai injection can increase the activity of the SOD in the blood of the patients with AMI and therefore have an active clinical significance in preventing these patients from the injury of reperfusion.