冻精人工授精的效果观察

THE RESULTS OF DONOR INSEMINATION WITH FROZEN SEMEN

采用冷冻精液供精行人工授精（ＡＩＤ）１０９例，共２０７个治疗周期。周期成功率为１３．５％，第１～３周期妊娠占总妊娠数的８２．１％。自然流产率为７．１％，出生婴儿发育均良好。影响ＡＩＤ成功的因素很多，本研究证实，成功组与失败组在精液质量及排卵监测方法上无显著差异（Ｐ＞０．０５）。经间痛可能有预告排卵，但成功组无１例有经间痛反应。实时超声监测排卵，方法简单，安全可靠。宫颈评分≥１０是授精的重要前提。黄体功能异常对ＡＩＤ的影响值得重视。

The results of therapy for 109 women who were inseminated with frozen donor semen are reported.In 207 treatment cycles,the monthly fecundability was 13.5% and the abortion rate was 7.1%. 23(82.1%) of pregnancy women began donor insemination in the first 3 months.Delivered infants are well-developed.Of factors affecting the success of donor insemination,semen quality and techniques for monitoring ovulation in conception group were not very different to those in nonconecption group (p>0.05).Mittelschmerz may be a sign of preovulation or ovulation, but there was no mittelschmerz in conception group. Real-time ultrasonography used to monitoring ovulation is a rapid, reliable method. For improving fecundability rates, Insler Cervical Score must be 10 point or above when donor insemination. It is very important to pay attention to the effects of malfunction of corpus luteum on the success of artificial insemination.