急性病毒性肝炎的血清病原分型及流行病学分析

The Prevalence of Different Types of Hepatitis in Patients with Acute Viral Hepatitis in Guizhou Area

对２１４例急性病毒性肝炎患者作病原学分型研究，并结合流行病学资料进行分析。结果，甲型为５６．５４％，乙型为１２．６％，甲、乙型混合感染为２．３４％，丙型为４．６７％，戊型为１０．２８％，１３．５５％未能分型，未发现有丁型。甲肝的平均发病年龄为２１岁，乙型、丙型与戊型分别为２７岁、３７岁和３３岁。各型肝炎均为男性多于女性，尤其是乙型和戊型。６１．４５％的甲肝发生在１０月至次年２月，而乙型、内型和戊型无明显季节性。甲肝、戊肝病人常有肠道暴露史而丙肝、乙肝病人肠外暴露较多见。

In order to investigate the prevalence of different types of viral hepatitis in Guizhou area,a serological and epidemiological survey of acute viral hepatitis in 214 cases was carried out.Serum specimens were tested by ELISA for specific antibody against HAV、HBc、HCV、NDV and HEV.The results showed that hepatitis A(HA) was diagriosed in 121 cases(56.54%),hepatitis B(HB)in 27 cases(12.6%),HA and HB mixted infection in 5 cases(2.34%),hepatitis C in 10 cases(4.67%),hepatitis E in 22 cases(10.28%),unidentification type of hepatitis could been found in 29 cases (13.55%).The age distribution of patients was that HA had a significantly younger median age (21 years old)than HB(27 years old),HC(37 years old) or HE(33 years old). As to other epidemiological data,there are some significant differences between the different types of hepatitis.