2Sanchez A,Tobyo M,Gonzalez L,et al.Biodegradable micro-and nanoparticles as long-term delivery vehicles for interferon-alpha[J].Eur J Pharm Sci,2003,18:221-229.
3Tracy MA,Bernstein H,Khan MA.Controlled release of metal cation-stabilized interferon:US,6379701[P].2002-04-30.
4Morita T,Horikiri Y,Yamahara H,et al.Formation and isolation of spherical fine protein microparticles through lyophilization of protein-poly(ethylene glycol) aqueous mixture[J].Pharm Res,2000,17:1367-1373.
5Singh M,Shirley B,Bajwa K,et al.Controlled release of recombinant insulin-like growth factor from a novel formulation of polylactide-co-glycolide microparticles[J].J Control Rel,2001,70:21-28.
6Johnson OL,Jaworowicz W,Cleland JL,et al.The stabilization and encapsulation of human growth hormone into biodegradable microspheres[J].Pharm Res,1997,14:730-735.
8Cleland JL,Jones AJS.Stable formulations of recombinant human growth hormone and interferon-γ for microencapsulation in biodegradable microspheres[J].Pharm Res,1996,13:1464-1475.
9Cleland JL.Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines[J].Biotechnol Prog,1998,14:102-107.
10Cleland JL,Duenas ET,Daugherty A,et al.Recombinant human growth hormone poly(lactic-co-glycolic acid)(PLGA) provide a long lasting effect[J].J Control Rel,1997,49:193-205.