手性亚砜的合成及其在不对称合成中的应用

Synthesis of Chiral Sulfoxides and Their Applications in Asymmetric Synthesis

本文综述了手性亚砜的合成。由于亚砜结构上的特征以及与金属离子的络合能力,使手性亚砜在不对称合成中具有强烈的诱导作用,使它成为进行不对称合成的一个手段。本文列举了它在不对称合成中的应用情况。

The methods of synthesis of chiral sulfoxide are reviewed. Owing to the characte- ristic structure and the coordinating capacity of sulfinyl group to metalic ions, chiral sulfo- xides exhibit strong asymmetric induction, Applications of chiral sulfoxides in asymmetric synthesis are summarized in this paper.