甾醇资源的利用和皮质激素侧链的合成方法

Exploitation of Sterol Resources and Synthetic Methods for the Corticoid Side Chain

本文讨论了开发甾醇资源作为甾体药物合成原料的前景,并综述了近几年由17-酮基甾体合成皮质激素侧链的各种方法。

In this review, the prospect of the exploitation of sterol resources as potentially useful starting material for the synthesis of steroid drugs is discussed and various synthetic methods for conversion of the steroidal 17-oxo group into the corticoid side chain develo- ped in recent years are summerized.