35年来肺心病患者肺部感染的病原菌变异的探讨

A Study in Variation Pathogenic Bacteria in Lung Infections of Patients with Cor Pulmonale within 35 Years

对３５年来肺心病肺部感染患者１４８９例痰菌培养结果分析，细菌的阳性率从１９７０年前的７７．９１％降至１９８０年后的５５．６１％。痰菌从球菌占８７．６３％转变为杆菌占４４．３７％，且多数为咽喉部常驻细菌。因此我们认为细菌对肺心病是感染过程，致敏过程抑或仅仅是一个继发作用，有待进一步探讨。临床证明，肺心病患者的呼吸道常有痉挛和不完全阻塞，一口痰和一次痰菌培养不能反映肺部感染的全貌，故建议对病人反复做菌前培养。

The analysis of 1 489 cases in recent 35 years showed the pcoitive rate of bacterial cultures of the sputum reduced from 77.91% in 1970 to 55.61% in 1980.The types of bacterin varied from cocci in the past(87.63%)to bacilli in recent years(44.17%)and these bacterin were almost normally staying in human throats.The results indicated that authors suggest which role do the bacteria play in the lung infection of the cor pulmonale patients? Is an infection course or a subseguent process? This meeds further research. Authors consider there are often spasm or obstruction in the respiratory tract of the paticnts,therefore a mouthful of phlegm or only once sputum culture cannot reflect the whole picture of the lung infection of the patients, so the bacterial cultures have to be repeated.