双冠醚的研究——Ⅳ.N,N-氨二乙酸类化合物与苯并-15-冠-5在多聚磷酸中生成亚甲基双(4'-苯并-15-冠-5)的反应

Studies on Bis(crown ether)s IV. Formation of Methylene Bis (4＇ -benzo-15-crown-5) from the Reaction of Some N,N-Aminodiacetic Acids arid Benzo-15-crown-5 in PPA

在多聚磷酸中,苯并冠醚与一元酸或二元酸反应,缩合而生成相应的酰基衍生物。本文用氨或胺衍生的N,N-胺二乙酸类化合物与苯并-15-冠-5和多聚磷酸相反应,探讨了这种体系的反应特点。所用的N。

Formation of methylene bis(4＇-benzo-15-erown-5) (1) has been accomplished by heating mixture of benzo-15-crown-5 and N, N- Aminodiacetic acid in polyphosphoric acid (PPA). The probable pathway of reaction is that the N, N-diacetic acids reacted with PPA at first to form the corresponding anhydrides, and then release CO_2 and CH_2O thermally. As a result, 1 was formed by the condensation of CH_2O with benzo-15-crown-5 unoer the action of PPA.