^(99m)TC-MIBI心肌断层显像潘生丁试验对缺血性心脏病诊断的评价

EVALUATION OF THE DIAGNOSIS OF ISCHEMIC HEART DISEASE BY^(99m)TC-MIBI MYOCARDIAL TOMOGRAPHIC IMAGING AFTER PERSANTIN TEST

本文对40例冠心病患者和32例正常人在潘生丁药物负荷前、后进行99mTc－MIBI心肌断层显像的资料进行了分析。结合潘生丁药物负荷前、后的99mTc－MIBI心肌断层图像和靶心图可对冠心病心肌缺血或心肌梗塞的部位、范围及严重程度作出有意义的评价，并可观察左室腔的大小和室壁厚薄等情况。其诊断冠心病的灵敏性为92．5％、特异性为87．5％。本文发现早期冠心病负荷显像表现的缺血区在静息状态下显像大多可恢复供血，其左室腔大小均正常，且无室壁增厚，此时普通心电图及心脏超声一般难以发现异常；而严重缺血或心肌梗塞在静息状态下显像，仅部份恢复或不恢复，部份病例并表现出左室心腔扩大及正常部位心肌代偿性增厚。

This paper reports 99m Tc-MIBI myocardial perfusion images of 40 cases of coronary artery disease (CAD) and 32 cases of normal subjects during persantin test and in rest by using single photon emission computered tomography (SPECT). The extent and severe scores in ischemic and infarcted area could be significantly evaluation by this myocardial tomographic imaging. Its sensitivity was 92.5% and specificity was 87.5% for diagnosis of CAD. Some patients of early CAD showed ischemic during stress test but they recovered normality in rest. Some patients of myocardial infarction and serious ischemic did not recover normality in rest.In the meantime some of the patients showed enlargement of left ventricle.