被动吸烟对豚鼠高空减压气泡生成影响的初步观察

A Preliminary Study of the Effect of Passive Smoking on Bubble Formation During Decompression in Guinea Pigs

观察了30只豚鼠于密闭舱内被动吸入卷烟烟雾(A组:1支,15 min;B组:2支,3min;C组:对照)对随后高空减压(13000m,停留20min)心前区气泡出现的影响.结果表明:在上述2种吸入卷烟烟雾的条件下,减压气泡的首次出现时间和气泡等级与对照组相比无显著差异(P>O05).初步提示减压暴露前短时间大量吸烟不会影响高空减压病的发生.

Effect of passive smoking on the precordial Doppler bubble grade were observed in 36 guinea pigs exposed to 13 000 m simulated altitude for 20 min. The guinea pigs were divided into 3 groups. A: inhaling smoke from 1 cigarette in a small chamber for 15 min;B:2 cigarettes, 30 min;C: control. Moving bubbles within the circulating blood were monitored by precordiol Etoppler ultrasound during the chamber exposure the bubble scores were graded according to Newman's method. The results showed that no significant change were observed in bubble grades and its appearance time in groups A and B as compared with group C(x = 2.9953 P>0.05). The results suggest that passive smoking just before exposure to altitude may not be a factor increasing the danger of bubble formation.