针刺镇痛时下橄榄核Fos样蛋白的表达

Expression of fos-like protein induced by electroacupuncture analgesia in nucleus olivaris inferior of rats

以Ｆｏｓ样蛋白作为神经元功能活动的标志，观察了大白鼠下橄榄核在伤害性刺激和针刺镇痛条件下Ｆｏｓ样蛋白阳性神经元数量的变化。发现伤害性刺激可引起下橄榄核Ｆｏｓ样蛋白阳性神经元数量显著增加（Ｐ＜０．０１）；而在针刺镇痛条件下，Ｆｏｓ样蛋白阳性神经元的数量又明显减少（Ｐ＜０．０１）。结果提示：下橄榄核可能参与了针刺镇痛机制的调节。

In this study, the position and the change of the number of positive neurons were observed under the condition of harmful stimulation and acupuncture analgesia in nucleus olivaris inferior in the rat by regarding fos-like protein as an immunopositive label for the function action of neurons. The results indicate that the number of the positive neurons of fos-like protein significantly increased in the group of harmful stimulation (P<0.01) and decreased obviously in the group of acupuncture analgesia(P<0.01). The results suggest that nucleus olivaris inferior may take part in the modulation of the mechanism in acupuncture analgesia.