22例生长激素缺乏症患儿生长激素释放激素刺激试验结果分析

ANALYSIS OF GHRH PROVOCTIVE TEST TO 22 PATIENTS SUFFERING FROM GH DEFICIENCY

本组对生长激素（ＧＨ）缺乏症患儿２２例进行了生长激素释放激素（ＧＨＲＨ）刺激试验，发现１２例（５４．５％）在注射ＧＨＲＨ后３０～６０ｍｉｎ的ＧＨ峰值显著升高（＞１０ｎｇ／ｍｌ），峰值范围为１０．７～３５．２ｎｇ／ｍｌ，平均１９．５ｎｇ／ｍｌ，表明在ＧＨ缺乏症患儿中，部分是由于下丘脑分泌的ＧＨＲＨ缺乏所致。

Growth hormone releasing hormone(GHRH)provoctive test was carried outin 22 children suffering from growth hormone(GH)deficiency. Levels of GH in excess of 10ng /ml was achieved in 12 children after injection of GHRH. The data suggest part of GH de-ficiency may result from GHRH deficiency.