原发性肝癌经腹肝动脉栓塞化疗与姑息性切除术的疗效比较

Treatment of Primary Liver Cancer via Laparotomic Transcatheter Arterial Chemoembolization Compared with Palliative Resection

本文对３２例原发性肝癌经腹肝动脉插管，使用碘油抗癌药物乳化液栓塞治疗，与４８例原发性肝癌行姑息性切除术进行比较分析。结果：栓塞化疗组与姑切组的ＡＦＰ转阴率、１年生存率、２年生存率分别为：８２．７％（２４／２９）与０，６２．５％（２０／３２）与２０．１％（１０／４８），３２．０％（８／２５）与０（Ｐ＜０．０５）。且栓塞化疗组３例获Ⅱ期根治性切除术．１例带瘤生存５４个月，至今健在。提示：对不能行根治性切除的肝癌，选用肝动脉插管栓塞化疗为佳。

Thirty two cases of primary liver cancer(PLC) were treated by laparotomic transcatheter arterial chemoembolization(TACE) using lipiodol mixed with anti-cancer drugs.They were compared with 48 cases of PLC who were performed palliative resection.The results showed:The rate of AFP level droped down to negative,1,2-year-survival rate in chemoembolization group and 1,2-year-survival rate in palliative resection group were 82.7% (24/29) and 0,62.5% (20/32) and 20.1%(10/48),32.0%(8/25)and 0(P<0.05) respectively.There were 3 cases in chemoembolization group which had a stage Ⅱ redical resection.1 case survived for 54 months and was still alive.It suggests that if the patient of PLC can't be performed redical hepatic resection,TACE is a better choice.