应用烟酸、胆碱和纤维素酶对围产期奶牛脂肪肝的防治研究

The use of nicotinic acid, choline and cellulase in the prevention andtreatment of fatty liver in periparlurient cow

给18头奶牛口服烟酸、胆碱和纤维素酶,并通过测定血液中游离脂肪酸(FFA)、谷草转氨酶(AST)和葡萄糖(Glu),监测受试牛肝脏的脂肪浸润程度,以提示上述三种药物对脂肪肝的防治效果。试验结果:预防组奶牛脂肪肝的发病率(22％)比对照组(44％)低;产后发病的平均时间(12.5d)较对照组(9.0d)晚;发病至康复时间(7.5d)也明显短于对照组(15d)。治疗组病牛肝脂肪浸润的平均治愈时间为13.6d,治愈率为100％。试验结果表明,口服烟酸,胆碱和纤维素酶对围产期奶牛脂肪肝有明显的预防和治疗作用。

Eighteen Chinese - Holstein dairy cows were given nicotinic acid,choline and cellulase orally during Periparturient period to treat andprevent fatty liver. Meanwhile, the concentrations of plasma free fattyacid,aspartate aminotramsferase(AST)and glucose were monitored in the cows.The results showed that the cows in the preventing group had alower(22/44%)incidence rate of fatty liver,a longer interval(12.5/9.0days) from calving to the occurrence of fatty liver and a shirter time(7.5/15days)of recorery compared with the cows in the control group.The cows in the treated group had a interval of 13.6 days in average forfat infiltration of the liver to recover and the trcovered rate was 100%.The results indicates that oral incotinic acid,chcline and cellulaseis very effective in the prevention and treatment of periparlunntfatty oiver in dairy cows.