摘要
研究了Ｎ－对甲苯磺酰基乙二胺与１，２－二溴乙烷的亲核取代反应，实验中使用过量的二溴乙烷反应，各次实验的主要产物都为Ｎ，Ｎ’－２对甲苯磺酰胺乙基四氢吡嗪，其产率达７４．６～８２％，本文还对实验结果进行了反应历程热力学分析．
The nucleophilic substitution reaction of N-tosylethylenediamine with 1,2-dibromoethane has several products. The nucleopilic substitution reaction is discussed in the paper. In experiments, the main products are N, N'-ditosylamidoethyltetrahydropyrazine in all experiments, Its yield ranges from 74.6～82%. The experiment results are analyzed from reaction mechanism and and thermodynamics.
关键词
亲核聚代反应
甲苯磺酰基
乙二胺
溴乙烷
Bifunctional radicals agent
N-alkylation reaction
Nucleophilic substitution reaction
Thermodynamic control reaction
