摘要
解热镇痛抗炎药致84例老年人急性胃粘膜病变(acutegastricmucosallesion,AGML)。其病理特征是胃十二指肠粘膜糜烂、水肿、出血,病灶多散在浅表不超过粘膜肌层。老年人多并发休克、心律失常、心绞痛和肺部感染等。急诊胃镜和粘膜活检有肯定的诊断价值。
Analysed were 84 cases of acute gastric mucosal lesion(AGML)caused by Analgesics and Anti-Inflammatroy drugs in old patients,The clinical manifestaions,including sporadic upper gastric bleeding,upper abdomen malaise,were often covered by the original diseases.Shock, arrhythmia,angina pectoris and lung infection were the common complications.Its pathological features were gastric-duodenal mucus edema,erosion and bleeding,only the mucosa of stamoch being affected,The diagnosis was made by emergency endoscopy and mucus biotopsy.We propose that old patients taking analgesics and Anti-Inflammatory drugs should be observed carefully and some preventional measures be adopted.
关键词
解热镇痛药
抗炎
胃粘膜病变
药物副作用
analgesics,anti-inflammatory/AE
gastric mucosa/DE
hemorrhage, gastrointestinal