摘要
对25例非胰岛素依赖型糖尿病(NIDDM)患者及24例正常人进行全套肺功能检查,并作对比分析,结果表明:NIDDM组比正常对照组V25/HT减低。差异有高度显著性(P<0.01);DLCO减低差异有显著性(P<0.05),并认为NIDDM患者小气道功能、弥散功能减低与糖代谢紊乱,致机体抵抗力降低、免疫功能下降,并与肺胞毛细血管基底膜增厚有关。检查NIDDM患者小气道功能和肺泡弥散功能,具有一定临床意义。
The pulmonary function was tested and analyesed comparatively in 25 cases of NIDDM patients and 24 healthy subjects respectively.The result showed that there was a remarkedly significant difference between NIDDM group and control group(P<0.01) in V25/HT and a significant difference in DLCO(P<0.05).It may be connected to abnormality of glucose metabolism, decrease of defence and immunity capacity,and the thicking of capillary basement membranes of pulmonary alveoli.Therefore,the tested ventilation small airway function(V25/HT) and diffusion capacity(DLLO) in NIDDM pts have some clinical significance.