101例急性脑血管病C－反应蛋白与血小板3因子的研究

Detection and Study of Acute Cerebrovascular Disease with C-reactive Protein and Activation of Platelet Factor 3

１０１例急性脑卒中患者的血清Ｃ－反应蛋白（ＣＲＰ）与血小板３因子（ＰＦ３）检测与研究结果表明，两项检查对脑出血与脑梗塞的鉴别有显著性意义，当急性期内ＣＲＰ检测明显增高而ＰＦ３的活动度在１１０％以上时，大致可确定为脑出血。而脑梗塞患者的ＣＲＰ与正常人无异且略低，ＰＦ３活动度一般在１００％以下。

It is very difficult to differentiate hemorragic from infarction stroke under the condition without CT scaning,we have detected 101 patients who had been admitted within 1 week after the onset of acute cerebrovascular disease. Both laboratory tests of serm C-reactive protein(CRP)and activation of platelet factor 3(PF3)are very slgnificant for differentiating hemorrhagic from infarction stroke.When C-reaction protein level increased in a short time or activation of the platelet factor 3 is more than 110%. The patient can be diagnosed as cerebral hemorrhage because the C·reactive protein level is the same as or lower than that of the control group and the activation of the platelet factor 3 was significantly lower(<100%).If the patients have cerebral infarction.Both detections are significant for patients'prognosis.The effects of the platelet's inhibiting function by CRP and PF3 is also discussed.