摘要
观测４０例慢性肺原性心脏病（肺心病）呼吸衰竭（呼衰）患者治疗前后（衰竭期和缓解期）血浆抗凝血酶Ⅲ抗原（ＡＴ－Ⅲ：Ａｇ）及纤维连接蛋白（ＦＮ）值的变化。结果表明，呼衰期（ｎ＝２２）ＡＴ－Ⅲ：Ａｇ和ＦＮ均明显降低（Ｐ＜０．０１），而缓解期（ｎ＝１８）与对照组（ｎ＝３１）比较，其变化差异无显著性。作者认为，ＡＴ－Ⅲ：Ａｇ和ＦＮ可作为临床上估计肺心病病情程度及其预后的指标；肺心病呼衰期使用抗凝剂很有必要。
mong 40 patients with chronic pulmonary heart
disease(CPHD),the changes of pe-ripheral blood antithrombin-Ⅲ antigen(AT-Ⅲ: Ag) and
fibronectin(FN ) in 22 patientswith respiratory failure and l8 with failure improved were
evaluated.It was found in failuregroupl AT-Ⅲ:Ag and FN were decreased significantly and in the
inlproved group they wereincreased. It suggests that both AT-Ⅲ: Ag and FN may be used to
identify the severe con-dition of respiratory failure of CPHD and Dipyridamole is necessary for
treatment of thesepatlents.
出处
《湖南医科大学学报》
CSCD
1995年第2期136-138,共3页
Bulletin of Hunan Medical University
