摘要
对４６例畸精症患者染色体及其配偶反复流产、死胎的情况进行了分析，发现１例常染色体易位，１１例伴有大Ｙ染色体，其大Ｙ发生率明显高于正常人群。伴有大Ｙ染色体的畸精症患者，其配偶流产或死胎的频率高于染色体正常的患者。表明畸精症、流产和兄胎的发生与Ｙ染色体的变异有关。
his paper analyzed chromosome in 46 teratozoospermic males and
incidence of recur-rent abortions or fetal deaths of their wives.One case of balanced autosomal
translocationand eleven cases of large Y were found.Incidence of large Y in
teratozoospermia(23.91%)was higher than that in normal population of China(11.18%).The
percent of recurrentabortions or fetal deaths in teratozoospermic males with large Y was higher
than that ofnormal chromosome group(P<0.05).It is speculated that the incidence of
teratozoospermiaand recurrent abortions or fetal deaths were related to heterochromatic
variants like largeY,and the variants likd large Y could be one of the causes of
teratozoospermia and play animportant role in recurrent abortions or fetal deaths related to
teratozoospermia.
出处
《湖南医科大学学报》
CSCD
1995年第3期269-271,共3页
Bulletin of Hunan Medical University
基金
湖南省卫生厅基金
关键词
染色体畸变
习惯性流产
死胎
畸精症
spermatozoa,abnormalities
chromosome
abnormalities
abortion,ha-bitual
fetal death
