摘要
随访１９８０年至１９９１年间胃癌前期病变８７９例，检出胃癌３４例，其中早期胃癌１４例。用流式细胞术（Ｆｌｏｗｃｙｔｏｍｅｔｒｙ，ＦＣＭ）检测４８例胃癌前病变细胞ＤＮＡ含量，检出非整倍体１６例，其中２例一年后发展为癌。本资料提示，胃镜与ＦＣＭ结合随访，更有利于胃癌的早期诊断。
ight hundred and seventy- nine cases of gastric precancerous lesions
diagnosed by en- doscope were followed up from 1980 to 1 991.Thirty- four patients with gastric
cancer werefound among whom 14 patients early gastric cancer(41.18%).Flow
cytometry(FCM)analy- sis was performed On 48 cases of gastric precancerous lesions in order
to study alteration ofcell nucleus DNA content,aneuploidy(33.3%)was detected in 16 cases
among whom 2 caseshad gastric cancer after one year follow- up,but none of the cases with
diploidy DNA becamecancer. These results suggest that gastroendoscopic examination and
FCM with follow- up are advantageous to the diagnosis of early gastric cancer.
出处
《湖南医科大学学报》
CSCD
1995年第6期591-593,共3页
Bulletin of Hunan Medical University
基金
湖南省卫生厅科研基金
关键词
原位癌
胃肿瘤
胃镜
流式细胞术
诊断
carcinoma in situ
stomach neoplasms
gastroscopy
flow cytome- try
follow- up
studies
diagnostic use
