摘要
报道黄连及其复方对人鼻咽癌细胞(HNE_1)的杀伤作用。黄连单用时作用最明显,半抑制浓度为1:729,具有浓度依赖性特点。与其它药配伍时,其作用稍减弱,半抑制浓度为1:249,兼浓度依赖性和时间依赖性两个特点。而去黄连的复方对HNE_1只有较弱的杀伤作用。半抑制浓度为1:27,具有时间依赖性特点。
This paper reported the action of Rhizoma Coptidis and its copmlex to killthe human nasopharyngeal cell(HNE1).Using Rhizoma Copidis only,the action is the mostobvious and the hemi-inhibitory concentration is 1:729,which means the action is dependenton the concentration. When the herb is combined with other medicines together,its action isreduced and the hemi-inhibitory concentration is 1:249,which implys the action is depen-dent on both concentration and time. When the herb is out of the complex,the complex is alittle effect to kill HNE1 and the hemi-inhibitory concentration is only 1:27,which suggeststhe action depends on the time.
出处
《湖南中医学院学报》
1995年第4期41-44,共4页
Journal of Hunan College of Traditional Chinese Medicine
基金
省中医药管理局资助课题
关键词
鼻咽肿瘤
中医药疗法
黄连
中药药理
动力学
Rhizoma Copidis/pharmacology
nasopharyngeal carcinoma/therapy ofTCM
@dynamics research