^（99m）Tc－NGA肝受体显像的临床初步应用

Preliminary Clinical Application of Liver Receptor Imaging of ￣( 99m)Tc-NGA

本文报告了２０例正常对照和３０例肝病患者（原发性肝癌１０例、慢性肝炎１５例、肝硬化５例）的９９ｍＴｃ－ＮＧＡ肝受体显你的结果。作者设计了一套肝受体显像综合诊断方案，包括系列动态摄取图象、药代动力学参数、ＨＥＦ、Ｔ９０和Ｔ９０参数显象，以定性评价肝受体的浓度和空间分布，定量评价肝功能方向性变化，定量评价总体肝功能（包括摄取量和摄取速度）和定量批价局部（每像素单元）肝功能。资料表明，该方法对肝占位性病变的诊断、功能栓肝细胞数量的估计和肝贮备功能的评价都有较大价值。

Twenty normal subjects and 30 patients with liver diseases underwent a 99mTc-NGA liver receptor imaging. We have designed A complete diagnostic plam of liver receptor imaging was designed, Including liver dynamic imaging. pharmacokinetic parameter,hepatocyte extriction fraction (HEF),T90 and local T90 parameter imaging.Thus,qualitive analysis of the concentration and spatial distribution of the liver receptor and quantitative evaluation of the whole and local tiver function could all be achieved. The rerults showed that the method was helpful not only in the diagnosis of liver occupying lesion and evaluation of the liver cell quantity, but also in the evaluation of liver storage functions.