一种测量视网膜锥体闪烁光ERG的改良方法──闪烁指数分析法

A Modified Method of Mesuring Cone Flicker Responses──Flicker Index Analytic Approach

闪烁光ＥＲＧ是反映视网膜锥体活动的客观指标。但在诸如视网膜色素变性等一些视锥功能处于高度受累的疾病，反应波形呈现非窦状，使用以往在分析中采用的峰－峰值测量法，则不能有效地反应出波形所代表的真切含义。本文根据病理状态下闪烁光反应的波形特点，特此提出一项测量闪烁光ＥＲＧ振幅的改良方法，即闪烁指数（ｆｌｉｃｋｅｒｉｎｄｅｘｔ．ＦＩ）分析法，并通过数学方法推导出一项闪烁指数测量公式以代替方格卡尺测量法。应用本法已在实践中获得良好的验证，从而认为应用此项方法可以准确、客观、迅速地测量得锥体闪烁光的反应状态，特别是在对锥体功能呈病理状态的一些视网膜疾病的观测。通过计算机程序化处理，ＦＩ分析法可为临床视觉电生理研究提供一种有效的手段。

formula for measuring the amplitudes of cone fliker ERG was presented by means of mathematical deduc-ing,to obtain the cone function information in the retina more scientifically,accurately and convieniently thanthose in the previous studies.The values being measured are termed″flicker index(FI)″.In some retinal diseaseswhich flicker responses not prasent sinusous,such as in the patients with retinits pigmentosa,the results shouldbe acquired easily and scientifically by way of FI measurement.The formula is: