摘要
心肌宁冲剂按相当成人日用量的70倍和35倍,大白鼠60只连续饲服8周,每周称重一次,并观察动物活动,毛发粪便情况,用药结束后,每组取10只动物,采血检查血常规,肝肾功能,取重要脏器进行病组组织学检查,结果未见明显毒性。
Xin Jining chongji was administered intra - gastrically to rats for 7 consecutive days in the dosages of 3.5g/kg/day, 1.75g/kg/day, and 0. 875g/kg/day respectively in 3 groups of rats. The results showed that Xin Jining chongji significantly antagonized the changes in electo-cardiogram and pathology of acute myocardial ischemia induced by isoproterenol in rats.