贾第虫研究──Ⅰ．西蒙氏贾第虫（Giardia　simoni）滋养体和包囊对实验动物的感染

STUDIES ON GIARDIA SPP.I.EXPERIMENTAL INIFECTION OF LABORATORY ANIMALS WITH TROPHOZOITES AND CYSTS OF GIARDIA SIMONI

作者从自然感染西蒙氏贾第虫（Ｇｉａｒｄｉａｓｉｍｏｎｉ）的金黄地鼠肠道内和粪便中分离、收集滋养体和包囊，分别经口感染大鼠、小鼠、豚鼠和兔子。结果表明兔子和脉鼠均不感染，大鼠、小鼠均不同程度地感染该虫，且４周龄大鼠比８周龄大鼠更易感（Ｐ＜０．０５），而在小鼠中成年鼠与老年鼠对西蒙氏贾第虫的敏感性没有差异（Ｐ＞０．０５）。滋养体在感染动物的肠道内主要分布于十二指肠前段，中前段和中段。同时观察到结肠和直肠内有包囊，这表明该虫在大鼠、小鼠体内完成了其生活史。作者还对感染前后的滋养体作了蛋白银和铁苏木精染色比较，二者在形态上完全相同。

A number of rats,mice, guinea pigs and rabbits were orally given trophozoites and cysts of Giardia simoni collected from naturally infected hamsters.The results showed that guinea pigs and rabbits resisted the infection of G.simoni,but rats and mice were infected.Young rats were more susceptible than adult rats to trophozoites and cysts.The trophozoites mainly distributed in anterior, mid-anterior and mid-part of the duodenum of the infected rats and mice.The cysts were found in the large intestine of the infected animals,indicating that G.simoni has completed its life cycle in rats and mice.The trophozoites from hamsters,rats and mice were morphologically compared after being stained with silver protein(protargol)and hematozylin.Observations showed that trophozoites were all identical in morphology.