复方甘草酸苷注射液治疗寻常型银屑病及湿疹皮炎的疗效观察

Observation on the efficacy of treatment using compound glycyrrhizin injection on psoriasis vulgaris and eczema dermatitis

目的:探讨复方甘草酸苷注射液治疗寻常型银屑病及湿疹皮炎的临床疗效。方法:选择60例寻常型银屑病及100例湿疹皮炎患者,分为治疗组和对照组,治疗组采用复方甘草酸苷注射液静脉注射加外用药,对照组仅外用药治疗。结果:寻常型进行期银屑病治疗组临床治愈率为43.3%,总有效率为86.7%,对照组临床治愈率为10.0%,总有效率为56.7%;湿疹皮炎治疗组临床治愈率为50.0%,总有效率为88.0%,对照组临床治愈率为10.0%,总有效率为68.0%。两治疗组在临床症状及体征改善方面明显优于对照组,差异具有显著统计学意义,且无明显副作用。结论:应用复方甘草酸苷注射液治疗寻常型银屑病及湿疹皮炎可明显提高临床疗效,不良反应轻微,值得进一步研究推广。

Objective To explore clinical effect of compound glycyrrhizin injection on psoriasis vulgaris and eczema dermatitis. Methods Sixty outpatients with progressive psoriasis vulgaris and 100 outpatients with eczema dermatitis were randomly divided into treatment group and control group. Compound glycyrrhizin injection was given intravenously combined with medicine for external application in treatment group; Medicine for external application was given only in control group. Results The clinical curative rate and total effective rate of psoriasis vulgaris in treatment group were 43.3% and 86.7% , in control group were 10. 0% and 56.7% , respoetively; Clinical curative rate and total effective rate of eczema dermatitis in treatment group were 50. 0 % and 88.0% , in control group were 10. 0% and 68.0% , respectively. Treatment group obviously surpassed control group in improving clinical symptoms and signs. There was obvious statistical significance, no serious adverse reactions. Conclusion Usage of compound glycyrrhizin injection for the treatment of psoriasis vulgaris and eczema dermatitis can greatly improve clinical curative effect, adverse reactions are slight, so this method should be further studied and spread.