影响慢性重型肝炎预后的因素分析

Analysis of prognostic factors for chronic severe hepatitis

目的探讨影响慢性重型肝炎预后的有关因素。方法分析78例慢性重型肝炎的预后与年龄、血清总胆红素、凝血酶原时间、凝血酶原活动度、总胆固醇、并发症、病毒重叠感染、有无肝硬化的关系。结果慢性重型肝炎的预后与血清总胆红素、凝血酶原时间、凝血酶原活动度、总胆固醇及并发症有关(P<0.01或P<0.05),而与年龄、病毒重叠感染、有无肝硬化无明显关系(P>0.05)。结论慢性重型肝炎患者血清总胆红素、凝血酶原时间、凝血酶原活动度、总胆固醇及并发症是判断预后的重要依据。

Objective To study the related factors influencing the prognosis of chronic severe hepatitis. Methods The prognosis was analyzed with respect to age, total serum bilirubin, prothrombin time, prothrombin activity, cholesterol, complications, virus superinfection, hepatic cirrhosis in 78 patients with chronic severe hepatitis. Results The prognosis of chronic severe hepatitis was correlated with total bilirubin, prothrombin time, prothrombin activity, cholesterol, and complications. Conclusion The total serum bilirubin, prothrombin time, prothrombin activity, cholesterol, and complications are important factors influencing prognosis.