异丙酚复合氯诺昔康用于人工流产术麻醉的研究

Propofol Combined with Lornoxican for Induced Abortion

目的评估异丙酚复合氯诺昔康用于人工流产术的麻醉效果与对患者术后宫缩疼痛情况的影响。方法100例门诊人工流产术患者,ASAI～II级,随机分为A和B组,每组50例,A组应用异丙酚1.5～2.5mg/kg,B组应用氯诺昔康8mg与异丙酚1.5～2.0mg/kg。监测呼吸频率、心率、无创动脉血压和脉搏氧饱和度,麻醉效果按优、良和差三级进行评定,采用视觉模拟评分法(VAS)对术后宫缩疼痛程度进行评估,记录术后患者苏醒时间及出现的副作用。结果两组间麻醉效果优良率和苏醒时间比较无统计学意义(P>0.05),宫缩痛程度B组较A组明显(P<0.01)。术后头晕头痛、恶心呕吐、呼吸抑制和异常出血等副作用组间比较无统计学意义(P>0.05)。结论异丙酚复合氯诺昔康麻醉下行人工流产术,术中和术后均可取得满意麻醉或镇痛效果,术后宫缩痛程度明显减轻,不延长术后苏醒时间。

Objective To evaluate the anesthesia effect of Propofol and Lornoxicam in inaucea abortion and the analgesic effect for postoperative uterine contraction, Methods lO0 cases, ASA Ⅰ-Ⅱ, induced abortion in outpatient service were randomly divided into group A and B （50 cases in each group）. Patients were used Propofol 1,5-2.5mg/kg in group A, and Propofol 1.5-2.0mg/ kg combined with Lornoxicam 8mg in group B. The respiration, heart rate, blood pressure, and Sp02 were observed routinely. The anesthesia effect were rated at 3 levels of excellent, good and bad, the degree of postoperative uterine contraction pain were evaluated by VAS. At the same time, to record postoperative awake time and the side effect, such as dizziness, headache, nausea, vomiting, dyspnea and abnormal bleeding, etc. Results There were no statistic significance in anesthesia effect and postoperative awake time between two groups（P〉0. 05）. The analgesia effect were better in group B than in group A （P〈0. O1）. There were no statistical significance in dizziness, headache, nausea, vomiting, dyspnea and abnormal bleeding （P〉0. 05）. Conclusion The anesthesia effects of Propofol combined with Lornoxicam used inducedl abortion, and the postoperative uterine contraction pain were decreased obviously. The postoperative awake time would not prolonged.