支撑架植入防止髓芯减压后狗股骨头塌陷的力学研究

Biomechanical effect of titanium alloy cage implantation for the center decompression of femoral head in dogs

[目的]对比研究单纯髓芯减压、髓芯减压+松质骨块移植、髓芯减压+支撑架植入治疗实验性狗股骨头坏死的生物力学行为。[方法]取新鲜狗股骨27对,随机分为3组,每组9对,每对股骨随机选取其中一侧,分别采用单纯髓芯减压、髓芯减压+松质骨块移植、髓芯减压+支撑架的方法进行处理,另一侧做正常对照,处理后进行股骨头力学性能测试,对实验结果标准化后进行统计学分析。[结果]单纯髓芯减压组和髓芯减压+松质骨块移植组的刚度及最大负载无明显差异,但其刚度及最大负载均明显低于正常组。髓芯减压+支撑架植入组股骨头的刚度及最大负载明显高于其他组。[结论]钛合金支撑架植入能够为股骨头负重区软骨下骨提供足够的机械支撑力,能起到防止股骨头塌陷,维持股骨头外形的作用。

[Objective ] To study the biomechanical effect of ischemic of the femoral head in dogs using titanium alloy cage, single core decompression, or decompression with bone grafting respectively. [Method] Twenty-seven couples of fresh dogs＇ femur specimens were divided randomly into 3 groups. One of every couple was used to manufacture core decompression model of femoral head. Biomechanical tested was made on every specimen in different conditions： core decompression, core decompression with bone grafting and titanium alloy cage implanting. The other of the couple was tested as normal control. [ Result] The stiffness and the max load of femoral head after titanium alloy cage implanting were much lager than that of the group 1 （core decompression） or the group 2 （core decompression with bone grafting） or the normal control. And the stiffness and the max load of the group 1 or the group 2 was less than that of the normal control. But there was not significant difference between group 1 and group 2. [ Conclusion ] The titanium alloy cage implanting could increase mechanical support and decrease the stress for femoral head significantly.